Radicores are the mutated descendants of manticores, and have adapted to the sub-zero environment of the Tundra. They have aspects of both lion, bat, and scorpion, showing sharp claws, fangs, and leathery wings. Their scorpion-like tails can deliver an extremely potent venom. The Tundra Flora and Fauna Guide notes that they are "radiation sponges", making their very presence dangerous. Any creature staying in extended proximity of a radicore, that isn't otherwise eaten, will eventually suffer severe radiation sickness.

Lozenge eventually weaponizes their venom sacs, and introduces a gaseous adaptation into the air supply during her raid on Amity Tower.